Identification of driver mutations in lung adenocarcinoma has led to development of targeted agents that are already approved for clinical use or are in clinical trials.Therefore, the number of biomarkers that will be needed to assess is expected to rapidly increase.This calls for the implementation of methods probing the mutational status of multi
Splicing is an important process for regulation of gene expression in eukaryotes, and it has important functional links to other steps of gene expression.Two examples of these linkages include Ceg1, a component of the mRNA capping enzyme, and the chromatin elongation factors Spt4-5, both of which have recently been shown to play a role in the norma
The article analyzes the research works devoted to the study of principles of management of patient safety.Used medical databases MEDLINE, Cochrane Collaboration, EMBASE, SCOPE, ISI Web of Science for the period 1991-2017.In most studies a Protein Snacks strict sequence of origin of the harm associated with healthcare management (adverse event or u
Abstract Background Increasing evidence suggests a critical role for long noncoding RNAs (LncRNAs) and pseudogenes in cancer.Renal cell carcinoma (RCC), the most common primary renal neoplasm, is highly aggressive and difficult to treat because of its resistance to chemotherapy and radiotherapy.Despite many identified LncRNAs and pseudogenes, few h